DONATE
GET HELP
SUPPORT
Facebook X-twitter Instagram Youtube
Facebook X-twitter Youtube
DONATE
GET HELP
SUPPORT
DONATE
GET HELP
SUPPORT
Facebook X-twitter Youtube

Diagnosis

Home

Diagnosis

How is it diagnosed?

Diagnosis is suspected clinically by patient history and examination. It is confirmed by EMG and nerve conduction tests. MRI of brain and spinal cord, lumbar puncture and blood tests are normal in MND and are done to exclude other diseases.

What is the prognosis?

Prognosis depends on the rate of progression of the disease. Rapidly progressive disease has poor prognosis. But the slow progressive can take several years course. Professor Stephen Hawking is a well-known example of a person with MND, and has lived for nearly 50 years with the disease. The television film Hawking starring Benedict Cumberbatch was made in 2004 about him and this disease. Also, in the year 2014 an Inspirational movie on Stephen Hawking named “THEORY OF EVERYTHING” gives positive hope for prognosis. Of all types PLS type has better prognosis and bulbar type has poor performance.

Will it get transmited to children of affected person?

If there is no family history, the disease will not be transmitted to their children. Their children will not be affected by the disease.

Symptom

Early stage

Progressive stage

Advanced stage

Speech disturbances
  • Increased effort of speech
  • Softening of voice after talking for sometime
  • Slurring of speech
  • Inability to speak for a long time with high fatigability
  • Inability to speak
  • Unintelligible speech
  • Complete loss of speech
Swallowing difficulty
  • Infrequent choking and coughing after drinking liquids
  • More frequent episodes of choking and coughing
  • Inability to swallow tablets
  • Inability to swallow solid food, food needs to mashed up
  • Inability to swallow
  • Considerable aspiration
  • Continuous drooling of saliva
Breathing difficulty
  • Heavy breathing physical activity
  • Feeling out of breath upon walking or climbing stairs
  • Feeling out of breath while eating, bathing and activities of daily living
  • Feeling out of breath upon lying in bed flat
  • Inability to breathe while talking for a longtime
  • Using neck muscles excessively while breathing
  • Inability to breathe without external device support
Drooling
  • Minimal drooling at night time
  • Drooling in posture with neck in flexion
  • General feeling of excess saliva in mouth
  • Considerable drooling throughout the day
  • Spitting of saliva while speaking and difficulty to swallow the excess saliva
  • Sticky, thick saliva
  • Inability to swallow the saliva
  • Continuous drooling
Facial muscle weakness
  • Twitching in the cheeks and chin
  • Spilling of water while gargling due to inability
  • Difficulty in opening the mouth
  • Affected facial expression
  • Facial asymmetry
  • Minimal opening of the mouth
Neck muscle weakness
  • Mild fasciculations in the neck region
  • Difficulty to lift the head up from supine
  • Difficulty holding the neck in the upright position
  • Difficulty lifting the head up after flexing the neck
  • Inability to look up in sitting position
  • Severe neck cramps
Fasciculations
  • Uncontrolled, sudden twitching of muscles
  • Increased frequency of twitching
  • Twitching of muscle in more
  • Reduced frequency of twitching in the body parts that have undergone

Symptom

1. Speech disturbances

Early stage
  • Increased effort of speech
  • Softening of voice after talking for sometime
Progressive stage
  • Slurring of speech
  • Inability to speak for a long time with high fatigability
  • Inability to speak
Advanced stage
  • Unintelligible speech
  • Complete loss of speech

2. Swallowing difficulty

Early stage
  • Infrequent choking and coughing after drinking liquids
Progressive stage
  • More frequent episodes of choking and coughing
  • Inability to swallow tablets
  • Inability to swallow solid food, food needs to mashed up
Advanced stage
  • Inability to swallow
  • Considerable aspiration
  • Continuous drooling of saliva

3. Breathing difficulty

Early stage
  • Heavy breathing physical activity
  • Feeling out of breath upon walking or climbing stairs
Progressive stage
  • Feeling out of breath while eating, bathing and activities of daily living
  • Feeling out of breath upon lying in bed flat
  • Inability to breathe while talking for a longtime
  • Using neck muscles excessively while breathing
Advanced stage
  • Inability to breathe without external device support

4. Drooling

Early stage
  • Minimal drooling at night time
  • Drooling in posture with neck in flexion
  • General feeling of excess saliva in mouth
Progressive stage
  • Considerable drooling throughout the day
  • Spitting of saliva while speaking and difficulty to swallow the excess saliva
Advanced stage
  • Sticky, thick saliva
  • Inability to swallow the saliva
  • Continuous drooling

5. Facial muscle weakness

Early stage
  • Twitching in the cheeks and chin
  • Spilling of water while gargling due to inability
Progressive stage
  • Difficulty in opening the mouth
  • Affected facial expression
Advanced stage
  • Facial asymmetry
  • Minimal opening of the mouth

6. Neck muscle weakness

Early stage
  • Mild fasciculations in the neck region
  • Difficulty to lift the head up from supine
Progressive stage
  • Difficulty holding the neck in the upright position
  • Difficulty lifting the head up after flexing the neck
Advanced stage
  • Inability to look up in sitting position
  • Severe neck cramps

7. Fasciculations

Early stage
  • Uncontrolled, sudden twitching of muscles
Progressive stage
  • Increased frequency of twitching
  • Twitching of muscle in more
Advanced stage
  • Reduced frequency of twitching in the body parts that have undergone

We are a dedicated group towards well being of people with MND and their families. We understand the difficult problems they have to face due to the disease. We are well aware of their special needs and challenges to be met. We support them in all possible ways.

Facebook X-twitter Instagram Youtube

Get in Touch

Donate Now
Supported by :

Quick Links

Addresses

Clinic Address :

Plot No: 19, Sector 40, Near Seawoods Grand Central Railway Station, Off, Palm Beach Rd, Seawoods, Navi Mumbai, Maharashtra 400706

Registered Address :
402, Guruprabha Apartment, S. B. Road, Dadar West, Mumbai – 400028, Maharashtra, India
Facebook X-twitter Instagram Youtube
Copyright ©2025 All rights reserved by Asha Ek Hope Foundation.
Designed, Maintained & SEO by

We are a dedicated group towards well being of people with MND and their families. We understand the difficult problems they have to face due to the disease. We are well aware of their special needs and challenges to be met. We support them in all possible ways.

Facebook X-twitter Instagram Youtube

Get in Touch

Donate Now

+91-9819741333

+91-8104546479

ashaekhope@gmail.com

Supported by :

Quick Links

Home

About Us

MND Clinic

Donate Now

Terms & Conditions

Privacy Policy

Addresses

Clinic Address :

Plot No: 19, Sector 40, Near Seawoods Grand Central Railway Station, Off, Palm Beach Rd, Seawoods, Navi Mumbai, Maharashtra 400706

Registered Address :
402, Guruprabha Apartment, S. B. Road, Dadar West, Mumbai – 400028, Maharashtra, India
Facebook X-twitter Youtube

We are a dedicated group towards well being of people with MND and their families. We understand the difficult problems they have to face due to the disease. We are well aware of their special needs and challenges to be met. We support them in all possible ways.

Facebook X-twitter Instagram Youtube

Get in Touch

Donate Now

+91-9819741333

+91-8104546479

ashaekhope@gmail.com

Supported by :

Quick Links

Home

About Us

MND Clinic

Donate Now

Terms & Conditions

Privacy Policy

Facebook X-twitter Youtube

Addresses

Clinic Address :

Plot No: 19, Sector 40, Near Seawoods Grand Central Railway Station, Off, Palm Beach Rd, Seawoods, Navi Mumbai, Maharashtra 400706

Registered Address :
402, Guruprabha Apartment, S. B. Road, Dadar West, Mumbai – 400028, Maharashtra, India
Copyright ©2025 All rights reserved by Asha Ek Hope Foundation.
Designed, Maintained & SEO by